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Bid (Ser61) Antibody, FITC Conjugated

Bid (Ser61) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, Bid (Ser61) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBid Ser61
SpecificityThis is a highly specific antibody against Bid Ser61
ModificationPhosphorylation
Modification siteSer61
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from mouse Bid around the phosphorylation site of Ser61
Gene ID number12122
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityMouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas, Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, In animal model studies, Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway, Mutation in the SH3 domain can diminish the cytochrome c releasing activity, The cytochrome c releasing activity of Bid was antagonized by Bcl2, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor, which in turn induces cytochrome c release and mitochondrial damage, Bid
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms AltName: BH3-interacting domain death agonist p15, BH3 interacting domain death agonist, BH3-interacting domain death agonist, BH3-interacting domain death agonist p11, BH3-interacting domain death agonist p13, BID, p-Bid phospho S61, p11 BID, p13 BID, p22 BID, Bid phospho S61
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBid (Ser61) Conjugated
Short name FITC Conjugated, Bid (Ser61) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, BH3 interacting domain death a this GO nist (Ser61) (Antibody to)
Alternative techniqueantibodies

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