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BIN2 Antibody, FITC Conjugated

BIN2 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, BIN2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBIN2
SpecificityThis is a highly specific antibody against BIN2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human BIN2/BRAP1
Gene ID number51411
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis, BIN1 also interacts with the transcription factors c-Myc and MyoD, BIN1 and BIN2 are BAR proteins that share 61% sequence similarity, BIN2, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region, BIN2 shows preferred expression in tissues of hematopoietic origin, In contrast to BIN1, There are two isoforms of BIN2 that are produced as a result of alternative splicing events, also known as Breast cancer-associated protein 1, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes, colon, is a 565 amino acid protein that interacts with BIN1, lymphoid and granulocytic cells, placenta, potentially functioning as a tumor suppressor, thymus, with high levels found in spleen, BAR proteins are characterized by a common N-terminal BAR (bin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms BRAP-1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBIN2 Conjugated
Short name FITC Conjugated, BIN2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, BIN2 (Antibody to)
Alternative techniqueantibodies
Identity 1053
Gene BIN2
Long gene name bridging integrator 2
Locus 12q13, 13
Discovery year 2000-05-25
GenBank acession AF146531
Entrez gene record 51411
Pubmed identfication 10903846
Classification N-BAR domain containing
Havana BLAST/BLAT OTTHUMG00000185197

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