| Alternative name1 | API2, Baculoviral IAP Repeat-containing 3, CIAP2, HAIP1, HIAP1, Inhibitor of Apoptosis 2, MIHC, TNFR2-TRAF Signaling Complex Protein), cIAP2, cellular, Anti-BIRC3 (IAP2 |
| Alternative name2 | API2, Baculoviral IAP Repeat-containing 3, CIAP2, HAIP1, HIAP1, Inhibitor of Apoptosis 2, MIHC, TNFR2-TRAF Signaling Complex Protein), cIAP2, cellular, BIRC3 (IAP2 |
| Alternative name3 | API2, Baculoviral IAP Repeat-containing 3, CIAP2, HAIP1, HIAP1, Inhibitor of Apoptosis 2, MIHC, TNFR2-TRAF Signaling Complex Protein), cIAP2, cellular, BIRC3 (IAP2 |
| Alternative name4 | BIRC3 |
| Alternative name5 | API2, Baculoviral IAP Repeat-containing 3, CIAP2, HAIP1, HIAP1, Inhibitor of Apoptosis 2, MIHC, TNFR2-TRAF Signaling Complex Protein), cIAP2, cellular, Anti -BIRC3 (IAP2 |
| Other names | API2, Apoptosis inhibitor 2, Baculoviral IAP repeat-containing protein 3, C-IAP2, IAP homolog C, IAP homolog C, IAP-1, IAP-1, Inhibitor of apoptosis protein 1, OTTHUMP00000235699, OTTHUMP00000235700, OTTHUMP00000235701, RING finger protein 49, RING finger protein 49, TNFR2-TRAF signaling complex protein, TNFR2-TRAF-signaling complex protein 1, TNFR2-TRAF-signaling complex protein 1, apoptosis inhibitor 2, baculoviral IAP repeat containing 3, baculoviral IAP repeat-containing 3, baculoviral IAP repeat-containing protein 3, hIAP-1, hIAP1, inhibitor of apoptosis protein 1, mammalian IAP homolog C, baculoviral IAP repeat-containing protein 3 |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | AIP1, API2, API2, BIRC3, CIAP2, HAIP1, HIAP1, IAP1, MALT2, MIHC, MIHC, RNF49, RNF49, c-IAP2, BIRC3 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | but does not appear to detect the mouse protein, Species Crossreactivity: Crossreacts with Human |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | 1, 5 mM sodium azide and 50% glycerol, PBS with 1 mg/ml BSA |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB), ELISA (EL/EIA) |
| Description | By understanding cell signaling, Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions, Errors in cellular information processing are responsible for diseases such as cancer, Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, activator, and diabetes, and immunity as well as normal tissue homeostasis, artificial tissues may be created, autoimmunity, caspase, diseases may be treated effectively and, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, theoretically, tissue repair, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | API2, Baculoviral IAP Repeat 3, CIAP2, HAIP1, HIAP1, Inhibitor of 2, MIHC, TNFR2-TRAF Signaling Complex Protein), cIAP2, cellular, BIRC3 (IAP2 |
| Short name | API2, Baculoviral IAP Repeat-containing 3, CIAP2, HAIP1, HIAP1, Inhibitor of Apoptosis 2, MIHC, TNFR2-TRAF Signaling Complex Protein) Antibody, cIAP2, cellular, BIRC3 (IAP2 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | API2, Baculoviral IAP Repeat-containing 3, CIAP2, HAIP1, HIAP1, MIHC, TNFR2-TRAF Signaling aggregate Protein) (Antibody to), cIAP2, cellular, suppressor on programmed cellular destruction 2, baculoviral IAP repeat containing 3 (IAP2 |
| Alternative technique | antibodies |
| Alternative to gene target | AIP1 and API2 and c-IAP2 and CIAP2 and HAIP1 and HIAP1 and MALT2 and MIHC and RNF49, BIRC3 and IDBG-629168 and ENSBTAG00000024918 and 514386, BIRC3 and IDBG-69045 and ENSG00000023445 and 330, Birc3 and IDBG-133177 and ENSMUSG00000032000 and 11796, ligase activity, nuclei, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0034121 and regulation of toll-like receptor signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0039535 and regulation of RIG-I signaling pathway and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0050727 and regulation of inflammatory response and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0060544 and regulation of necroptotic process and biological process this GO :0060546 and negative regulation of necroptotic process and biological process this GO :0070266 and necroptotic process and biological process this GO :0070424 and regulation of nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :2000116 and regulation of cysteine-type endopeptidase activity and biological process this GO :2000378 and negative regulation of reactive oxygen species metabolic process and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, baculoviral IAP repeat containing 3 |
| Identity | 591 |
| Gene | BIRC3 |
| Long gene name | baculoviral IAP repeat containing 3 |
| Synonyms gene | API2 |
| Synonyms gene name | baculoviral IAP repeat-containing 3 |
| Synonyms | cIAP2 hiap-1 MIHC RNF49 MALT2 c-IAP2 |
| Synonyms name | apoptosis inhibitor 2 TNFR2-TRAF signaling complex protein mammalian IAP homolog C inhibitor of apoptosis protein 1 |
| Locus | 11q22, 2 |
| Discovery year | 1998-06-10 |
| GenBank acession | L49432 |
| Entrez gene record | 330 |
| Pubmed identfication | 8552191 8548810 |
| RefSeq identity | NM_001165 |
| Classification | Baculoviral IAP repeat containing Ring finger proteins Caspase recruitment domain containing |
| Havana BLAST/BLAT | OTTHUMG00000167324 |
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