| Also known as | BIRC5 |
| Other names | Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Baculoviral IAP repeat-containing protein 5, apoptosis inhibitor 4, apoptosis inhibitor survivin, baculoviral IAP repeat containing 5, baculoviral IAP repeat-containing protein 5, survivin variant 3 alpha, baculoviral IAP repeat-containing protein 5 isoform 1 |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | BIRC5 |
| Gene name synonims | N/A |
| Other gene names | API4, API4, BIRC5, EPR-1, IAP4, BIRC5 |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG1 |
| Clone | 2D3 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method | BIRC5 antibody was purified by affinity chromatography |
| Form/Appearance | 50% glycerol and 0, containing 1% BSA, pH 7, 02% sodium azide, 3, Supplied in PBS buffer |
| Concentration | 500 ug-1 miligram per 1 mililiter |
| Storage and shipping | Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies, Long term storage should be done after aliquoting and at -20°, thus reducing their activity, C, For shorter periods of time keep the antibody at +4 degrees Celsius |
| Tested applications: | Immunofluorescence (IF), Western Blot (WB), Flow Cytometry (FC) |
| French translation | anticorps |
| Gene target | BIRC5 |
| Short name | BIRC5 antibody |
| Alternative name | baculoviral IAP repeat containing 5 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | API4 and EPR-1, BIRC5 and IDBG-642915 and ENSBTAG00000013573 and 414925, BIRC5 and IDBG-70554 and ENSG00000089685 and 332, Birc5 and IDBG-214593 and ENSMUSG00000017716 and 11799, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007059 and chromosome segregation and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0008017 and microtubule binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008536 and Ran GTPase binding and molecular function this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0015631 and tubulin binding and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030496 and midbody and cellular component this GO :0031021 and interphase microtubule organizing center and cellular component this GO :0031503 and protein complex localization and biological process this GO :0031536 and positive regulation of exit from mitosis and biological process this GO :0031577 and spindle checkpoint and biological process this GO :0032133 and chromosome passenger complex and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048037 and cofactor binding and molecular function this GO :0050897 and cobalt ion binding and molecular function this GO :0051087 and chaperone binding and molecular function this GO :0051301 and cell division and biological process this GO :0051303 and establishment of chromosome localization and biological process this GO :0061178 and regulation of insulin secretion involved in cellular response to glucose stimulus and biological process this GO :0061469 and regulation of type B pancreatic cell proliferation and biological process, centromeric region and cellular component this GO :0000777 and condensed chromosome kinetochore and cellular component this GO :0000910 and cytokinesis and biological process this GO :0004869 and cysteine-type endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005814 and centriole and cellular component this GO :0005819 and spindle and cellular component this GO :0005829 and cytosol and cellular component this GO :0005874 and microtubule and cellular component this GO :0005876 and spindle microtubule and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0006351 and transcription, chaperone binding, nuclei, this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000226 and microtubule cytoskeleton organization and biological process this GO :0000228 and nuclear chromosome and cellular component this GO :0000278 and mitotic cell cycle and biological process this GO :0000775 and chromosome, this GO :0004869: cysteine-type endopeptidase inhibitor activity, this GO :0004869: cysteine-type endopeptidase inhibitor activity and also this GO :0005515: protein binding and also this GO :0008017: microtubule binding and also this GO :0008270: zinc ion binding and also this GO :0008536: Ran GTPase binding and also this GO :0015631: tubulin binding and also this GO :0019899: enzyme binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process and also this GO :0046872: metal ion binding and also this GO :0046982: protein heterodimerization activity and also this GO :0048037: cofactor binding and also this GO :0050897: cobalt ion binding and also this GO :0051087: chaperone binding, this GO :0005515: protein binding, this GO :0008017: microtubule binding, this GO :0008270: zinc ion binding, this GO :0008536: Ran GTPase binding, this GO :0015631: tubulin binding, this GO :0019899: enzyme binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0046872: metal ion binding, this GO :0046982: protein heterodimerization activity, this GO :0048037: cofactor binding, this GO :0050897: cobalt ion binding, this GO :0051087: chaperone binding, baculoviral IAP repeat containing 5 |
| Identity | 593 |
| Gene | BIRC5 |
| Long gene name | baculoviral IAP repeat containing 5 |
| Synonyms gene | API4 |
| Synonyms gene name | apoptosis inhibitor 4 baculoviral IAP repeat-containing 5 |
| Synonyms | EPR-1 survivin |
| Synonyms name | survivin variant 3 alpha |
| Locus | 17q25, 3 |
| Discovery year | 1998-06-10 |
| GenBank acession | U75285 |
| Entrez gene record | 332 |
| Pubmed identfication | 8106347 7947793 |
| RefSeq identity | NM_001168 |
| Classification | Baculoviral IAP repeat containing Chromosomal passenger complex |
| Havana BLAST/BLAT | OTTHUMG00000177505 |
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