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BMP10 Antibody, Cy3 Conjugated

BMP10 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, BMP10 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBMP10
SpecificityThis is a highly specific antibody against BMP10
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range350-400/424
Subcellular locationSecreted
SourceKLH conjugated synthetic peptide derived from human BMP10
Gene ID number27302
Swiss ProtO95393
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, Inhibits endothelial cell migration and growth, May reduce cell migration and cell matrix adhesion in breast cancer cell lines, SMAD5 and SMAD8 transcription factors, leading to activation of SMAD1, Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Properties 1 of the BMP10 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBMP10 Conjugated
Short name Conjugated, BMP10 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, bone morphogenetic protein 10 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BMP10 and IDBG-54663 and ENSG00000163217 and 27302, BT, Bmp10 and IDBG-165762 and ENSMUSG00000030046 and 12154, DNA-templated and biological process this GO :0055009 and atrial cardiac muscle tissue morphogenesis and biological process this GO :0055010 and ventricular cardiac muscle tissue morphogenesis and biological process this GO :0055015 and ventricular cardiac muscle cell development and biological process this GO :0055117 and regulation of cardiac muscle contraction and biological process this GO :0060038 and cardiac muscle cell proliferation and biological process this GO :0060045 and positive regulation of cardiac muscle cell proliferation and biological process this GO :0060298 and positive regulation of sarcomere organization and biological process this GO :0060347 and heart trabecula formation and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :2000138 and positive regulation of cell proliferation involved in heart morphogenesis and biological process, Extracellular, receptor serine/threonine kinase binding, this GO :0005125 and cytokine activity and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007507 and heart development and biological process this GO :0007512 and adult heart development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0009986 and cell surface and cellular component this GO :0010596 and negative regulation of endothelial cell migration and biological process this GO :0010613 and positive regulation of cardiac muscle hypertrophy and biological process this GO :0010614 and negative regulation of cardiac muscle hypertrophy and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0014898 and cardiac muscle hypertrophy in response to stress and biological process this GO :0030018 and Z disc and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0033612 and receptor serine/threonine kinase binding and molecular function this GO :0040007 and growth and biological process this GO :0045214 and sarcomere organization and biological process this GO :0045893 and positive regulation of transcription, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005179: hormone activity and also this GO :0005515: protein binding and also this GO :0008083: growth factor activity and also this GO :0033612: receptor serine/threonine kinase binding, this GO :0005179: hormone activity, this GO :0005515: protein binding, this GO :0008083: growth factor activity, this GO :0033612: receptor serine/threonine kinase binding, 106443 and IDBG-635729 and ENSBTAG00000000992 and 538874, bone morphogenetic protein 10
Identity 20869
Gene BMP10
Long gene name bone morphogenetic protein 10
Locus 2p13, 3
Discovery year 2003-04-16
GenBank acession AF101441
Entrez gene record 27302
Pubmed identfication 10072785
RefSeq identity NM_014482
Classification Endogenous ligands Bone morphogenetic proteins
Havana BLAST/BLAT OTTHUMG00000129573
Locus Specific Databases LRG_403

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