| Long name | BMPR1A Primary Polyclonal Antibody |
| Also known as | BMPR1A PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | BMPR1A/CD292 |
| Specificity | This is a highly specific antibody against BMPR1A/CD292 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 90-130/532 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BMPR-1A |
| Gene ID number | 657 |
| Swiss Prot | P36894 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Receptor for BMP-2 and BMP-4, Type II receptors phosphorylate and activate type I receptors which autophosphorylate, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases, then bind and activate SMAD transcriptional regulators, On ligand binding |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 10q23del, ACVRLK3, ALK-3, Activin receptor-like kinase 3, BMP type-1A receptor, BMPR-1A, BMPR1A, Bone morphogenetic protein receptor type-1A, CD292, SKR5, Serine/threonine-protein kinase receptor R5, ALK3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BMPR1A |
| Short name | BMPR1A Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | classification IA (Antibody to), bone morphogenetic protein receptor |
| Alternative technique | antibodies |
| Alternative to gene target | 10q23del and ACVRLK3 and ALK3 and CD292 and SKR5, BMPR1A and IDBG-81081 and ENSG00000107779 and 657, BT, Bmpr1a and IDBG-149689 and ENSMUSG00000021796 and 12166, Cell surfaces, DNA-templated and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048339 and paraxial mesoderm development and biological process this GO :0048352 and paraxial mesoderm structural organization and biological process this GO :0048368 and lateral mesoderm development and biological process this GO :0048378 and regulation of lateral mesodermal cell fate specification and biological process this GO :0048382 and mesendoderm development and biological process this GO :0048568 and embryonic organ development and biological process this GO :0048589 and developmental growth and biological process this GO :0048598 and embryonic morphogenesis and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050768 and negative regulation of neurogenesis and biological process this GO :0051216 and cartilage development and biological process this GO :0060021 and palate development and biological process this GO :0060391 and positive regulation of SMAD protein import into nucleus and biological process this GO :0060896 and neural plate pattern specification and biological process this GO :0060914 and heart formation and biological process, this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0001707 and mesoderm formation and biological process this GO :0001756 and somitogenesis and biological process this GO :0001880 and Mullerian duct regression and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003272 and endocardial cushion formation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005901 and caveola and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006955 and immune response and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007389 and pattern specification process and biological process this GO :0007398 and ectoderm development and biological process this GO :0007399 and nervous system development and biological process this GO :0007492 and endoderm development and biological process this GO :0007507 and heart development and biological process this GO :0009950 and dorsal/ventral axis specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0014032 and neural crest cell development and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004675: transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702: receptor signaling protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005024: transforming growth factor beta-activated receptor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004675: transmembrane receptor protein serine/threonine kinase activity, this GO :0004702: receptor signaling protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005024: transforming growth factor beta-activated receptor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0042803: protein homodimerization activity, this GO :0046332: SMAD binding, this GO :0046872: metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0042803: protein homodimerization activity and also this GO :0046332: SMAD binding and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0019827 and stem cell maintenance and biological process this GO :0021983 and pituitary gland development and biological process this GO :0021998 and neural plate mediolateral regionalization and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030154 and cell differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030425 and dendrite and cellular component this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0035137 and hindlimb morphogenesis and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045893 and positive regulation of transcription, type IA, 48514 and IDBG-631434 and ENSBTAG00000000231 and 404101, bone morphogenetic protein receptor |
| Identity | 1076 |
| Gene | BMPR1A |
| Long gene name | bone morphogenetic protein receptor type 1A |
| Synonyms gene | ACVRLK3 |
| Synonyms gene name | bone morphogenetic protein receptor, type IA |
| Synonyms | ALK3 CD292 |
| Locus | 10q23, 2 |
| Discovery year | 1994-12-12 |
| GenBank acession | BC028383 |
| Entrez gene record | 657 |
| Pubmed identfication | 8397373 9730621 |
| RefSeq identity | NM_004329 |
| Classification | Type 1 receptor serine/threonine kinases CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000018657 |
| Locus Specific Databases | LRG_298 |