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BNIP3L Antibody

BNIP3L Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBNIP3L Primary Polyclonal Antibody
Also known asBNIP3L PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBNIP3L
SpecificityThis is a highly specific antibody against BNIP3L
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range170-219/219
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BNIP3L
Gene ID number665
Swiss ProtO60238
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix, Can overcome the suppressors BCL-2 and BCL-XL, Inhibits apoptosis induced by BNIP3, Interacts with viral and cellular anti-apoptosis proteins, Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, May function as a tumor suppressor, The physical interaction of SPATA18/MIEAP, although high levels of BCL-XL expression will inhibit apoptosis, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria, Induces apoptosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Adenovirus E1B19K-binding protein B5, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, BNIP3H, BNIP3L, BNIP3a, NIP3-like protein X, NIP3L, NIX
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBNIP3L
Short nameBNIP3L Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameB-cell CLL/lymphoma 2/adenovirus E1B 19kDa interacting protein 3-like (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BNIP3L and IDBG-13074 and ENSG00000104765 and 665, BNIP3L and IDBG-635626 and ENSBTAG00000021307 and 534615, BNIP3a and NIX, Bnip3l and IDBG-175760 and ENSMUSG00000022051 and 100043324, nuclei, protein heterodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005521 and lamin binding and molecular function this GO :0005635 and nuclear envelope and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005740 and mitochondrial envelope and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031224 and intrinsic component of membrane and cellular component this GO :0035694 and mitochondrial protein catabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051607 and defense response to virus and biological process this GO :0097345 and mitochondrial outer membrane permeabilization and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005521: lamin binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0046982: protein heterodimerization activity, this GO :0005521: lamin binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0046982: protein heterodimerization activity, 12177, 102641641, BCL2/adenovirus E1B 19kDa interacting protein 3-like
Identity 1085
Gene BNIP3L
Long gene name BCL2 interacting protein 3 like
Synonyms gene name BCL2/adenovirus E1B 19kDa interacting protein 3 like
Synonyms Nix BNIP3a
Locus 8p21, 2
Discovery year 1997-07-01
GenBank acession AB004788
Entrez gene record 665
Pubmed identfication 9523198 9973195
RefSeq identity NM_004331
Havana BLAST/BLAT OTTHUMG00000099433

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