Name : BNIP3L Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3783965061
| Long name | ALEXA FLUOR 647 Conjugated, BNIP3L Polyclonal Antibody |
| Also known as | Anti-BNIP3L PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BNIP3L |
| Specificity | This is a highly specific antibody against BNIP3L |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 170-219/219 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BNIP3L |
| Gene ID Number | 665 |
| Swiss Prot | O60238 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix, Can overcome the suppressors BCL-2 and BCL-XL, Inhibits apoptosis induced by BNIP3, Interacts with viral and cellular anti-apoptosis proteins, Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, May function as a tumor suppressor, The physical interaction of SPATA18/MIEAP, although high levels of BCL-XL expression will inhibit apoptosis, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria, Induces apoptosis |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | Nix BNIP3a |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the BNIP3L Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | BNIP3L |
| Short name | BNIP3L Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, B-cell CLL/lymphoma 2/adenovirus E1B 19kDa interacting protein 3-like (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BNIP3L and IDBG-13074 and ENSG00000104765 and 665, BNIP3L and IDBG-635626 and ENSBTAG00000021307 and 534615, BNIP3a and NIX, Bnip3l and IDBG-175760 and ENSMUSG00000022051 and 100043324, nuclei, protein heterodimerization activity, this GO :0005515 and protein binding and molecular function this GO :0005521 and lamin binding and molecular function this GO :0005635 and nuclear envelope and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005740 and mitochondrial envelope and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031224 and intrinsic component of membrane and cellular component this GO :0035694 and mitochondrial protein catabolic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0051607 and defense response to virus and biological process this GO :0097345 and mitochondrial outer membrane permeabilization and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0005521: lamin binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0046982: protein heterodimerization activity, this GO :0005521: lamin binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0046982: protein heterodimerization activity, 12177, 102641641, BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| Identity | 1085 |
| Gene | BNIP3L |
| Long gene name | BCL2 interacting protein 3 like |
| Synonyms gene name | BCL2/adenovirus E1B 19kDa interacting protein 3 like |
| Locus | 8p21, 2 |
| Discovery year | 1997-07-01 |
| GenBank acession | AB004788 |
| Entrez gene record | 665 |
| Pubmed identfication | 9523198 9973195 |
| RefSeq identity | NM_004331 |
| Havana BLAST/BLAT | OTTHUMG00000099433 |