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BOP1 Antibody

BOP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBOP1 Primary Polyclonal Antibody
Also known asBOP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBOP1
SpecificityThis is a highly specific antibody against BOP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BOP1
Gene ID number23246
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis, BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, Deregulation of BOP1 may lead to colorectal tumorigenesis, The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits, This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit, Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5, as well as a deficit in the cytosolic 60S ribosomal subunit, thereby affecting rRNA maturation and the cell cycle, 8S rRNA synthesis, Predominantly localized to the nucleolus
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AW146150, BOP1_HUMAN, Block of proliferation 1, Block of proliferation 1 protein, Bop1, Bop1 block of proliferation 1, D18861, Erb1p, Kiaa0124, MGC109114, Ribosome biogenesis protein BOP1, mKIAA0124, AU020183
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBOP1
Short nameBOP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBOP1 (Antibody to)
Alternative techniqueantibodies
Identity 15519
Gene BOP1
Long gene name block of proliferation 1
Synonyms KIAA0124
Locus 8q24, 3
Discovery year 2001-08-28
GenBank acession AK024840
Entrez gene record 23246
Pubmed identfication 8590280
RefSeq identity NM_015201
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000174603

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