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BOP1 Antibody, ALEXA FLUOR 594

BOP1 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, BOP1 Polyclonal Antibody
Also known asAnti-BOP1 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBOP1
SpecificityThis is a highly specific antibody against BOP1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BOP1
Gene ID Number23246
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis, BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, Deregulation of BOP1 may lead to colorectal tumorigenesis, The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits, This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit, Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5, as well as a deficit in the cytosolic 60S ribosomal subunit, thereby affecting rRNA maturation and the cell cycle, 8S rRNA synthesis, Predominantly localized to the nucleolus
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms KIAA0124
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetBOP1
Short nameBOP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, BOP1 (Antibody to)
Alternative techniqueantibodies
Identity 15519
Gene BOP1
Long gene name block of proliferation 1
Locus 8q24, 3
Discovery year 2001-08-28
GenBank acession AK024840
Entrez gene record 23246
Pubmed identfication 8590280
RefSeq identity NM_015201
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000174603

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