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BORA Antibody, ALEXA FLUOR 594

BORA Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, BORA Polyclonal Antibody
Also known asAnti-BORA PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBORA
SpecificityThis is a highly specific antibody against BORA
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BORA
Gene ID Number79866
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Bora (protein aurora borealis) is a 559 amino acid protein that activates ARK-1, Bora is localized to the nucleus until mitosis is initiated, Downregulation of the gene encoding Bora results in multipolar spindles in mitosis, It is through this mechanism that Bora and ARK-1 control cellular mitotic entry, Plk (polo-like kinase) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation on its N-terminus by ARK-1, This translocation is dependent on activated Cdc2, a phenomenon that is also observed when ARK-1 function is blocked, bipolar spindle assembly and chromosome segregation during mitosis, when it then translocates to the cytoplasm, which releases Bora to bind and activate ARK-1 in the cytoplasm, Aurora related kinase-1 (ARK-1) is a centrosome-associated serine/threonine kinase that regulates centrosome separation
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms FLJ22624
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetBORA
Short nameBORA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, BORA (Antibody to)
Alternative techniqueantibodies
Identity 24724
Gene BORA
Long gene name aurora kinase A activator , bora
Synonyms gene C13orf34
Synonyms gene name chromosome 13 open reading frame 34
Locus 13q21, 33
Discovery year 2006-08-15
GenBank acession BC025367
Entrez gene record 79866
Pubmed identfication 16890155 18378770 18566290 19487276
RefSeq identity NM_024808
Havana BLAST/BLAT OTTHUMG00000017068

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