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BORA Antibody, Biotin Conjugated

BORA Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, BORA Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBORA
SpecificityThis is a highly specific antibody against BORA
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human BORA
Gene ID number79866
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Bora (protein aurora borealis) is a 559 amino acid protein that activates ARK-1, Bora is localized to the nucleus until mitosis is initiated, Downregulation of the gene encoding Bora results in multipolar spindles in mitosis, It is through this mechanism that Bora and ARK-1 control cellular mitotic entry, Plk (polo-like kinase) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation on its N-terminus by ARK-1, This translocation is dependent on activated Cdc2, a phenomenon that is also observed when ARK-1 function is blocked, bipolar spindle assembly and chromosome segregation during mitosis, when it then translocates to the cytoplasm, which releases Bora to bind and activate ARK-1 in the cytoplasm, Aurora related kinase-1 (ARK-1) is a centrosome-associated serine/threonine kinase that regulates centrosome separation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FLJ22624
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetBORA Conjugated
Short name Conjugated, BORA Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, BORA (Antibody to)
Alternative techniqueantibodies
Identity 24724
Gene BORA
Long gene name aurora kinase A activator , bora
Synonyms gene C13orf34
Synonyms gene name chromosome 13 open reading frame 34
Locus 13q21, 33
Discovery year 2006-08-15
GenBank acession BC025367
Entrez gene record 79866
Pubmed identfication 16890155 18378770 18566290 19487276
RefSeq identity NM_024808
Havana BLAST/BLAT OTTHUMG00000017068

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