Name : BORA Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8222726697
| Long name | Cy7 Conjugated, BORA Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BORA |
| Specificity | This is a highly specific antibody against BORA |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human BORA |
| Gene ID number | 79866 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Bora (protein aurora borealis) is a 559 amino acid protein that activates ARK-1, Bora is localized to the nucleus until mitosis is initiated, Downregulation of the gene encoding Bora results in multipolar spindles in mitosis, It is through this mechanism that Bora and ARK-1 control cellular mitotic entry, Plk (polo-like kinase) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation on its N-terminus by ARK-1, This translocation is dependent on activated Cdc2, a phenomenon that is also observed when ARK-1 function is blocked, bipolar spindle assembly and chromosome segregation during mitosis, when it then translocates to the cytoplasm, which releases Bora to bind and activate ARK-1 in the cytoplasm, Aurora related kinase-1 (ARK-1) is a centrosome-associated serine/threonine kinase that regulates centrosome separation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | FLJ22624 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | BORA Conjugated |
| Short name | Conjugated, BORA Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, BORA (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24724 |
| Gene | BORA |
| Long gene name | aurora kinase A activator , bora |
| Synonyms gene | C13orf34 |
| Synonyms gene name | chromosome 13 open reading frame 34 |
| Locus | 13q21, 33 |
| Discovery year | 2006-08-15 |
| GenBank acession | BC025367 |
| Entrez gene record | 79866 |
| Pubmed identfication | 16890155 18378770 18566290 19487276 |
| RefSeq identity | NM_024808 |
| Havana BLAST/BLAT | OTTHUMG00000017068 |