| Long name | Recombinant Bovine Bile acid receptor (NR1H4) |
| Alternative names | Bile acid receptor, Farnesoid X-activated receptor, Farnesol receptor HRR-1, Nuclear receptor subfamily 1 group H member 4, bile acid receptor, farnesoid X-activated receptor, farnesol receptor HRR-1, group H, member 4<, nuclear receptor subfamily 1, nuclear receptor subfamily 1 group H member 4, bile acid receptor |
| Gene name | NR1H4 |
| Other gene names | NR1H4, NR1H4 |
| General description | All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Bile acid receptor(NR1H4) is a recombinant protein expressed in Baculovirus |
| Product category | Recombinant Proteins |
| Expression system | Baculovirus |
| Available also expressed in: | Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity | Greater than 90% (determined by SDS-PAGE) |
| Form | Lyophilized protein |
| Storage | Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications | IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Description | 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target | Bile acid receptor (NR1H4) |
| Short name | Bile acid receptor (NR1H4) |
| Species | Bos Taurus genes are available form the Bovine Genome database, Bovine |
| Alternative name | family H, member 4), Bovine Bile acid receptor (nuclear receptor subfamily 1 |
| Alternative to gene target | BAR and FXR and HRR-1 and HRR1 and RIP14, BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0007165 and signal transduction and biological process this GO :0008206 and bile acid metabolic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009749 and response to glucose and biological process this GO :0010467 and gene expression and biological process this GO :0016922 and ligand-dependent nuclear receptor binding and molecular function this GO :0030522 and intracellular receptor signaling pathway and biological process this GO :0032052 and bile acid binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034255 and regulation of urea metabolic process and biological process this GO :0038181 and bile acid receptor activity and molecular function this GO :0038185 and intracellular bile acid receptor signaling pathway and biological process this GO :0042277 and peptide binding and molecular function this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046965 and retinoid X receptor binding and molecular function this GO :0048565 and digestive tract development and biological process this GO :0070857 and regulation of bile acid biosynthetic process and biological process this GO :0070858 and negative regulation of bile acid biosynthetic process and biological process this GO :0071229 and cellular response to acid and biological process this GO :0071417 and cellular response to organonitrogen compound and biological process this GO :0090181 and regulation of cholesterol metabolic process and biological process this GO :1902122 and chenodeoxycholic acid binding and molecular function this GO :2000213 and positive regulation of glutamate metabolic process and biological process this GO :2001250 and positive regulation of ammonia assimilation cycle and biological process, NR1H4 and IDBG-52872 and ENSG00000012504 and 9971, Nr1h4 and IDBG-184281 and ENSMUSG00000047638 and 20186, chenodeoxycholic acid binding, group H, member 4, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001080 and nitrogen catabolite activation of transcription from RNA polymerase II promoter and biological process this GO :0001190 and RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0004887 and thyroid hormone receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005719 and nuclear euchromatin and cellular component this GO :0006109 and regulation of carbohydrate metabolic process and biological process this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001190: RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0003707: steroid hormone receptor activity and also this GO :0003713: transcription coactivator activity and also this GO :0003714: transcription corepressor activity and also this GO :0004872: receptor activity and also this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0004887: thyroid hormone receptor activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016922: ligand-dependent nuclear receptor binding and also this GO :0032052: bile acid binding and also this GO :0038181: bile acid receptor activity and also this GO :0042277: peptide binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0046965: retinoid X receptor binding and also this GO :1902122: chenodeoxycholic acid binding, this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001190: RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0003707: steroid hormone receptor activity, this GO :0003713: transcription coactivator activity, this GO :0003714: transcription corepressor activity, this GO :0004872: receptor activity, this GO :0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0004887: thyroid hormone receptor activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016922: ligand-dependent nuclear receptor binding, this GO :0032052: bile acid binding, this GO :0038181: bile acid receptor activity, this GO :0042277: peptide binding, this GO :0043565: sequence-specific DNA binding, this GO :0046965: retinoid X receptor binding, this GO :1902122: chenodeoxycholic acid binding, 48865 and IDBG-636894 and ENSBTAG00000013596 and 540528, nuclear receptor subfamily 1 |
| Identity | 7967 |
| Gene | NR1H4 |
| Long gene name | nuclear receptor subfamily 1 group H member 4 |
| Synonyms gene name | group H, member 4 , nuclear receptor subfamily 1 |
| Synonyms | FXR RIP14 HRR1 HRR-1 |
| Synonyms name | farnesoid X receptor |
| Locus | 12q23, 1 |
| Discovery year | 1999-09-17 |
| GenBank acession | U68233 |
| Entrez gene record | 9971 |
| Pubmed identfication | 7774010 9223286 |
| RefSeq identity | NM_005123 |
| Classification | Nuclear hormone receptors |
| Havana BLAST/BLAT | OTTHUMG00000170359 |
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