Name : BPI Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6421245215
| Long name | BPI Primary Polyclonal Antibody |
| Also known as | BPI PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | BPI |
| Specificity | This is a highly specific antibody against BPI |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BPI |
| Gene ID number | 671 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 2) neutralization of gram-negative bacterial LPS, 3) opsonization of bacteria to enhance phagocytosis by neutrophils, Binding of BPI to live bacteria via LPS causes anti-infective activites: 1) cytotoxicity via sequential damage to bacterial outer and inner lipid membranes, The cytotoxicity action of BPI is limited to gram negative bacteria, reflecting the high affinity of BPI for bacterial LPS, The antimicrobial protein Bactericidal Permeability Increasing protein (BPI) is a 55 kDa protein found in the primary granules of polymorhonuclear leukocytes (PMN) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BPI, BPI_HUMAN, CAP 57, bactericidal/permeability-increasing protein, Bactericidal permeability-increasing protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | BPI |
| Short name | BPI Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | bactericidal/permeability-increasing protein (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BPI and IDBG-642592 and ENSBTAG00000014046 and 280734, BPI and IDBG-74654 and ENSG00000101425 and 149684, BPIFD1 and rBPI, Bpi and IDBG-211473 and ENSMUSG00000052922 and 329547, Plasma membranes, lipid binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0008289 and lipid binding and molecular function this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032717 and negative regulation of interleukin-8 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0043031 and negative regulation of macrophage activation and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001530: lipopolysaccharide binding, this GO :0001530: lipopolysaccharide binding and also this GO :0008289: lipid binding, this GO :0008289: lipid binding, 671, bactericidal/permeability-increasing protein |
| Identity | 1095 |
| Gene | BPI |
| Long gene name | bactericidal/permeability-increasing protein |
| Synonyms | BPIFD1 |
| Synonyms name | BPI fold containing family D, member 1 |
| Locus | 20q11, 23 |
| Discovery year | 1992-03-13 |
| GenBank acession | J04739 |
| Entrez gene record | 671 |
| Pubmed identfication | 8432532 |
| RefSeq identity | NM_001725 |
| Classification | BPI fold containing |
| Havana BLAST/BLAT | OTTHUMG00000032441 |