Name : BRAF35 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1779909020
| Long name | ALEXA FLUOR 647 Conjugated, BRAF35 Polyclonal Antibody |
| Also known as | Anti-BRAF35 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BRAF35 |
| Specificity | This is a highly specific antibody against BRAF35 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BRAF35 |
| Gene ID Number | 10362 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A second breast cancer susceptibility gene, BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns, BRCA2, BRCA2 does not confer a substantially elevated risk of ovarian cancer, Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer, The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation, The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain, also confers a high incidence of breast cancer, but unlike BRCA1, located on chromosome 13q12-13, which associates with condensed chromatin during histone H3 phosphorylation, The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | SOXL HMGX2 BRAF35 SMARCE1r BRAF25 HMGXB2 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the BRAF35 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | BRAF35 |
| Short name | BRAF35 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, BRAF35 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 5002 |
| Gene | HMG20B |
| Long gene name | high mobility group 20B |
| Synonyms gene name | high-mobility group 20B |
| Synonyms name | HMG box domain containing 2 |
| Locus | 19p13, 3 |
| Discovery year | 1999-06-11 |
| GenBank acession | BC003505 |
| Entrez gene record | 10362 |
| Pubmed identfication | 10773667 |
| RefSeq identity | NM_006339 |
| Classification | Non-canonical high mobility group |
| Havana BLAST/BLAT | OTTHUMG00000150437 |