Name : BRAF35 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN2216999795
| Long name | Cy7 Conjugated, BRAF35 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | BRAF35 |
| Specificity | This is a highly specific antibody against BRAF35 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human BRAF35 |
| Gene ID number | 10362 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A second breast cancer susceptibility gene, BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns, BRCA2, BRCA2 does not confer a substantially elevated risk of ovarian cancer, Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer, The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation, The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain, also confers a high incidence of breast cancer, but unlike BRCA1, located on chromosome 13q12-13, which associates with condensed chromatin during histone H3 phosphorylation, The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | SOXL HMGX2 BRAF35 SMARCE1r BRAF25 HMGXB2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | BRAF35 Conjugated |
| Short name | Conjugated, BRAF35 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, BRAF35 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 5002 |
| Gene | HMG20B |
| Long gene name | high mobility group 20B |
| Synonyms gene name | high-mobility group 20B |
| Synonyms name | HMG box domain containing 2 |
| Locus | 19p13, 3 |
| Discovery year | 1999-06-11 |
| GenBank acession | BC003505 |
| Entrez gene record | 10362 |
| Pubmed identfication | 10773667 |
| RefSeq identity | NM_006339 |
| Classification | Non-canonical high mobility group |
| Havana BLAST/BLAT | OTTHUMG00000150437 |