Filters

Brain1/POU3F3 Antibody

Brain1/POU3F3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBrain1/POU3F3 Primary Polyclonal Antibody
Also known asBrain1/POU3F3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBrain1/POU3F3
SpecificityThis is a highly specific antibody against Brain1/POU3F3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Brain1/POU3F3
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Brn-1 and Brn-2 appear to critically control the initiation of radial migration of cortical neurons, Brn-1 and Brn-2 are class III POU domain proteins, Brn-2 is thought to be involved in smooth muscle cell development and differentiation, Brn-3 is a class IV POU domain protein, Brn-3a has two functional transactivating domains, Brn-3b, Brn-3b and Brn-3c, Brn-3b generally functions as a transcriptional repressor, Expressed during the development of the forebrain and coexpressed in most layer II-V cortical neurons, However, Three Brn-3 proteins have been described and are designated Brn-3a, While Brn-3a and Brn-3c stimulate transcription, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor, one at the amino terminus and one at the carboxy terminus, The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BRN 1, BRN1, Brain specic homeobox/POU domain protein 1, Brain-1, Brain-specic homeobox/POU domain protein 1, Brain1, Brn-1, OTF 8, OTF-8, OTF8, Oct-8, Octamer-binding protein 8, Octamer-binding transcription factor 8, PO3 F3, PO3F 3, PO3F3, PO3F3_HUMAN, POU class 3 homeobox 3, POU domain, POU domain, POU3 F3, POU3F 3, Pou3f3, RHS 1, RHS1, Rhs 2, Rhs2, Skin 1, Skin1, class 3, class 3, transcription factor 3, transcription factor 3, Brain 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBrain1/POU3F3
Short nameBrain1/POU3F3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBrain1/POU class 3 homeobox 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BRN1 and OTF8, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007417 and central nervous system development and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0021799 and cerebral cortex radially oriented cell migration and biological process this GO :0021869 and forebrain ventricular zone progenitor cell division and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0071837 and HMG box domain binding and molecular function this GO :0072218 and metanephric ascending thin limb development and biological process this GO :0072227 and metanephric macula densa development and biological process this GO :0072233 and metanephric thick ascending limb development and biological process this GO :0072236 and metanephric loop of Henle development and biological process this GO :0072240 and metanephric DCT cell differentiation and biological process, HMG box domain binding, POU3F3 and IDBG-64389 and ENSG00000198914 and 5455, Pou3f3 and IDBG-149164 and ENSMUSG00000045515 and 18993, nuclei, this GO :0001822 and kidney development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0071837: HMG box domain binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0043565: sequence-specific DNA binding, this GO :0071837: HMG box domain binding, POU class 3 homeobox 3
Identity 9216
Gene POU3F3
Long gene name POU class 3 homeobox 3
Synonyms gene name POU domain class 3, transcription factor 3
Synonyms BRN1 OTF8
Locus 2q12, 1
Discovery year 1995-03-17
Entrez gene record 5455
Classification POU class homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000153067

Similar products

Subscribe to our Newsletter