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BRCC36 Antibody, ALEXA FLUOR 594

BRCC36 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, BRCC36 Polyclonal Antibody
Also known asAnti-BRCC36 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBRCC36
SpecificityThis is a highly specific antibody against BRCC36
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BRCC3/BRCC36
Gene ID Number79184
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Catalytic subunit of the BRISC complex, Component of the BRCA1-A complex, Does not have activity toward 'Lys-48'-linked polyubiquitin chains, In the BRCA1-A complex, Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates, antagonizing the RNF8-dependent ubiquitination at double-strand breaks (DSBs), it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs), via the interaction of the BRISC complex with the CSN complex, Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms C6, 1A BRCC36
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetBRCC36
Short nameBRCC36 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, BRCC36 (Antibody to)
Alternative techniqueantibodies
Identity 24185
Gene BRCC3
Long gene name BRCA1/BRCA2-containing complex subunit 3
Synonyms gene CXorf53
Synonyms gene name chromosome X open reading frame 53 BRCA1/BRCA2-containing complex, subunit 3
Synonyms name Lys-63-specific deubiquitinase
Locus Xq28
Discovery year 2004-12-03
GenBank acession X64643
Entrez gene record 79184
Pubmed identfication 1303175 14636569
RefSeq identity NM_024332
Classification BRISC complex BRCA1 A complex
Havana BLAST/BLAT OTTHUMG00000022658

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