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BRCC45 Antibody, ALEXA FLUOR 488

BRCC45 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, BRCC45 Polyclonal Antibody
Also known asAnti-BRCC45 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenBRCC45
SpecificityThis is a highly specific antibody against BRCC45
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BRCC45
Gene ID Number9577
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen At least three isoforms of BRCC45 are known to exist, BRCC45 has also been suggested to function as a death receptor associated anti apoptotic protein by inhibiting the BID induced activation of the mitochondrial apoptotic pathway, Higher levels of BRCC45 were detected in the majority of hepatocellular carcinomas, Later experiments indicated BRCC45 forms a complex with the breast and ovarian predisposition proteins BRCA1 and BRCA2 as well as RAD51 and BRCC36, This complex has a ubiquitin E3 ligase activity and is thought to enhance cellular survival following DNA damage, suggesting that BRCC45 may promote tumorigenesis when overexpressed, BRCC45 was initially suggested to be a housekeeping protein that is highly expressed in brain and reproductive organs
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms BRCC45 BRCC4
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the BRCC45 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetBRCC45
Short nameBRCC45 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, BRCC45 (Antibody to)
Alternative techniqueantibodies
Identity 1106
Gene BRE
Long gene name brain and reproductive organ-expressed (TNFRSF1A modulator)
Synonyms name BRCA1/BRCA2-containing complex, subunit 4
Locus 2p23, 2
Discovery year 1999-04-23
GenBank acession AF015767
Entrez gene record 9577
Pubmed identfication 9737713 7826398
Classification BRISC complex BRCA1 A complex
Havana BLAST/BLAT OTTHUMG00000097831

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