c-Abl Antibody

c-Abl Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	c-Abl Primary Polyclonal Antibody
Also known as	c-Abl PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	c-Abl
Specificity	This is a highly specific antibody against c-Abl
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Subcellular location	Secreted
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human c-Abl
Gene ID number	25
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Activity of c-Abl protein is negatively regulated by its SH3 domain, The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, The t(9, [provided by RefSeq], and deletion of the SH3 domain turns ABL1 into an oncogene, and stress response, cell adhesion, cell division, suggesting a cell cycle function for ABL1, with alternatively spliced first exons spliced to the common exons 2-11, 22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia, The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	ABL, ABL1_HUMAN, Abelson murine leukemia viral v abl oncogene homolog 1, Abl 1, Abl protein, Abl1, Abl1, Bcr/c abl oncogene protein, JTK 7, JTK7, Proto oncogene tyrosine protein kinase ABL1, Transformation gene oncogene ABL, p150, v abl, v abl Abelson murine leukemia viral oncogene homolog 1, Abelson Murine Leukemia Viral Oncogene Homolog 1
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	c-Abl
Short name	c-Abl Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	c-Abl (Antibody to)
Alternative technique	antibodies
Identity	76
Gene	ABL1
Long gene name	ABL proto-oncogene 1, non-receptor tyrosine kinase
Synonyms gene	ABL
Synonyms gene name	non-receptor tyrosine kinase , receptor tyrosine kinase c-abl oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1 c-abl oncogene 1
Synonyms	JTK7 c-ABL p150
Locus	9q34, 12
Discovery year	1986-01-01
GenBank acession	M14752
Entrez gene record	25
Pubmed identfication	1857987 12626632
RefSeq identity	NM_007313
Classification	SH2 domain containing
Havana BLAST/BLAT	OTTHUMG00000020813
Locus Specific Databases	LRG_769

c-Abl Antibody

c-Abl Antibody size: 0.1ml 263

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