Name : c-Abl Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5088330942
| Long name | ALEXA FLUOR 350 Conjugated, c-Abl Polyclonal Antibody |
| Also known as | Anti-c-Abl PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | c-Abl |
| Specificity | This is a highly specific antibody against c-Abl |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human c-Abl |
| Gene ID Number | 25 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activity of c-Abl protein is negatively regulated by its SH3 domain, The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, The t(9, [provided by RefSeq], and deletion of the SH3 domain turns ABL1 into an oncogene, and stress response, cell adhesion, cell division, suggesting a cell cycle function for ABL1, with alternatively spliced first exons spliced to the common exons 2-11, 22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia, The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | JTK7 c-ABL p150 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | c-Abl |
| Short name | c-Abl Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, c-Abl (Antibody to) |
| Alternative technique | antibodies |
| Identity | 76 |
| Gene | ABL1 |
| Long gene name | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| Synonyms gene | ABL |
| Synonyms gene name | non-receptor tyrosine kinase , receptor tyrosine kinase c-abl oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1 c-abl oncogene 1 |
| Locus | 9q34, 12 |
| Discovery year | 1986-01-01 |
| GenBank acession | M14752 |
| Entrez gene record | 25 |
| Pubmed identfication | 1857987 12626632 |
| RefSeq identity | NM_007313 |
| Classification | SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000020813 |
| Locus Specific Databases | LRG_769 |