Name : c-Kit Antibody (CD117)
Supplier : NJS POLY
Price :199
SKU : GEN8607988997
| Category | Antibody |
| Concentration | 09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | c-Kit (CD117) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Primate , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the cKit antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This cKit antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P10721 |
| Purity | Purified |
| Description | [UniProt], and in melanogenesis, gametogenesis, hematopoiesis, mast cell development, migration and function, stem cell maintenance, c-Kit is a Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation |
| Immunogen | A portion of amino acids 9-40 from the human protein was used as the immunogen for this cKit antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the cKit antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | c-Kit (CD117) |
| Short name | c-Kit Antibody (CD117) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | c-reagent (Antibody to) (CD117) |
| Alternative technique | antibodies |
| Identity | 6342 |
| Gene | KIT |
| Long gene name | KIT proto-oncogene receptor tyrosine kinase |
| Synonyms gene | PBT |
| Synonyms gene name | piebald trait v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| Synonyms | CD117 SCFR C-Kit |
| Locus | 4q12 |
| Discovery year | 1986-01-01 |
| GenBank acession | S67773 |
| Entrez gene record | 3815 |
| Pubmed identfication | 9027509 |
| RefSeq identity | NM_000222 |
| Classification | CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000128713 |
| Locus Specific Databases | LRG_307 |