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c-Kit Antibody, Cy7 Conjugated

c-Kit Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, c-Kit Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenc-Kit
SpecificityThis is a highly specific antibody against c-Kit
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range928-964/988
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human CD117/c-kit
Gene ID number3815
Swiss ProtP10721
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Dog, Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activated KIT also transmits signals via GRB2 and activation of RAS, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1, CBL, CRK (isoform Crk-II), In response to KITLG/SCF binding, KIT can activate several signaling pathways, KIT signaling is modulated by protein phosphatases, LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, PLCG1, Phosphorylates PIK3R1, Promotes activation of STAT family members STAT1, Promotes phosphorylation of PIK3R1, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, SH2B2/APS and CBL, SRC and SHC1, STAT3, STAT3, STAT5A and STAT5B, STAT5A and STAT5B, and by rapid internalization and degradation of the receptor, and in melanogenesis, and of the transcription factors STAT1, gametogenesis, hematopoiesis, mast cell development, migration and function, stem cell maintenance, the regulatory subunit of phosphatidylinositol 3-kinase, 4, 5-trisphosphate, Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms C-Kit, CD117, KIT, Mast/stem cell growth factor receptor Kit, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PBT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetc-Kit Conjugated
Short name Conjugated, c-Kit Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, c-reagent (Antibody to)
Alternative techniqueantibodies

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