c-Maf Antibody

c-Maf Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	c-Maf Primary Polyclonal Antibody
Also known as	c-Maf PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	c-Maf
Specificity	This is a highly specific antibody against c-Maf
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen range	270-320/373
Subcellular location	Nucleus
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human c-Maf
Gene ID number	4094
Swiss Prot	O75444
Tested Applications	FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions	FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Activates the expression of IL4 in T helper 2 (Th2) cells, Activates transcription of the CD13 proximal promoter in endothelial cells, Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity), Binds element G1 on the glucagon promoter, Binds to the ARE sites of detoxifying enzyme gene promoters, Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters, Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter, Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression, Involved either as an oncogene or as a tumor suppressor, Involved in embryonic lens fiber cell development, Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development, Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation, Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction, Together with PAX6, When overexpressed, depending on the cell context, represses anti-oxidant response element (ARE)-mediated transcription, transactivates strongly the glucagon gene promoter through the G1 element, Acts as a transcriptional activator or repressor
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	MAF, Proto-oncogene c-Maf, Transcription factor Maf, V-maf musculoaponeurotic fibrosarcoma oncogene homolog, c-MAF, CCA4
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	c-Maf
Short name	c-Maf Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	c-Maf (Antibody to)
Alternative technique	antibodies
Identity	24319
Gene	CMIP
Long gene name	c-Maf inducing protein
Locus	16q23, 2-q23, 3
Discovery year	2011-08-04
GenBank acession	AB051481
Entrez gene record	80790
Pubmed identfication	11214970 12939343
RefSeq identity	NM_030629
Havana BLAST/BLAT	OTTHUMG00000176520

c-Maf Antibody

c-Maf Antibody size: 0.1ml 263

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