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c-Maf Antibody, ALEXA FLUOR 488

c-Maf Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, c-Maf Polyclonal Antibody
Also known asAnti-c-Maf PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenc-Maf
SpecificityThis is a highly specific antibody against c-Maf
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range270-320/373
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human c-Maf
Gene ID Number4094
Swiss ProtO75444
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Activates the expression of IL4 in T helper 2 (Th2) cells, Activates transcription of the CD13 proximal promoter in endothelial cells, Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity), Binds element G1 on the glucagon promoter, Binds to the ARE sites of detoxifying enzyme gene promoters, Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters, Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter, Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression, Involved either as an oncogene or as a tumor suppressor, Involved in embryonic lens fiber cell development, Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development, Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation, Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction, Together with PAX6, When overexpressed, depending on the cell context, represses anti-oxidant response element (ARE)-mediated transcription, transactivates strongly the glucagon gene promoter through the G1 element, Acts as a transcriptional activator or repressor
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the c-Maf Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetc-Maf
Short namec-Maf Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, c-Maf (Antibody to)
Alternative techniqueantibodies
Identity 24319
Gene CMIP
Long gene name c-Maf inducing protein
Locus 16q23, 2-q23, 3
Discovery year 2011-08-04
GenBank acession AB051481
Entrez gene record 80790
Pubmed identfication 11214970 12939343
RefSeq identity NM_030629
Havana BLAST/BLAT OTTHUMG00000176520

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