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c-Maf Antibody, Biotin Conjugated

c-Maf Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, c-Maf Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenc-Maf
SpecificityThis is a highly specific antibody against c-Maf
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range270-320/373
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human c-Maf
Gene ID number4094
Swiss ProtO75444
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activates the expression of IL4 in T helper 2 (Th2) cells, Activates transcription of the CD13 proximal promoter in endothelial cells, Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity), Binds element G1 on the glucagon promoter, Binds to the ARE sites of detoxifying enzyme gene promoters, Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters, Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter, Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression, Involved either as an oncogene or as a tumor suppressor, Involved in embryonic lens fiber cell development, Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development, Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation, Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction, Together with PAX6, When overexpressed, depending on the cell context, represses anti-oxidant response element (ARE)-mediated transcription, transactivates strongly the glucagon gene promoter through the G1 element, Acts as a transcriptional activator or repressor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MAF, Proto-oncogene c-Maf, Transcription factor Maf, V-maf musculoaponeurotic fibrosarcoma oncogene homolog, c-MAF, CCA4
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetc-Maf Conjugated
Short name Conjugated, c-Maf Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, c-Maf (Antibody to)
Alternative techniqueantibodies

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