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c-Raf(Tyr341) Antibody, Cy5.5 Conjugated

c-Raf(Tyr341) Antibody, Cy5.5 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, c-Raf(Tyr341) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenc-Raf Tyr341
SpecificityThis is a highly specific antibody against c-Raf Tyr341
ModificationPhosphorylation
Modification siteTyr341
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range325-375/648
Subcellular location Cell membrane, Mitochondrion, Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Tyr341
Gene ID number5894
Swiss ProtP04049
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ADCY5 and ADCY6, Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death, Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity, Phosphorylates TNNT2/cardiac muscle troponin T, Phosphorylates adenylyl cyclases: ADCY2, Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2), Regulates Rho signaling and migration, Restricts caspase activation in response to selected stimuli, The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, and erythroid differentiation, and is required for normal wound healing, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, apoptosis, apoptosis (MAP3K5/ASK1 and STK3/MST2), by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75', differentiation, notably Fas stimulation, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, pathogen-mediated macrophage apoptosis, proliferation and angiogenesis (RB1), resulting in their activation, survival and oncogenic transformation, which induces down-regulation of OCLN, Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms CMD1NN, CRAF, Proto-oncogene c-RAF, RAF, RAF proto-oncogene serine/threonine-protein kinase, RAF1, Raf-1, c-Raf, NS5
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetc-Raf(Tyr341) Conjugated
Short name Conjugated, c-Raf(Tyr341) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, c-Raf(Tyr341) (Antibody to)
Alternative techniqueantibodies

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