Name : C-rel (318CT41.3.2) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :328
SKU : GEN8014271202
| Long name | 2) Monoclonal Antibody, 3, C-rel (318CT41 |
| Also known as | 2) Monoclonal Antibody, 3, C-rel (318CT41 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | C-rel |
| Specificity | This is a highly specific antibody against C-rel |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 2, 3, 318CT41 |
| Source | This REL monoclonal antibody is generated from mouse immunized with REL recombinant protein |
| Gene ID number | 5966 |
| Swiss Prot | Q04864 |
| Tested Applications | IF, WB |
| Recommended dilutions | IF(1:10~50), WB(1:500~16000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Different dimer combinations act as transcriptional activators or repressors, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, In a conventional activation pathway, NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family, NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52, RELB, The NF-kappa-B heterodimer RELA/p65-c-Rel is a transcriptional activator, The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity, cell growth, differentiation, immunity, respectively, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus, tumorigenesis and apoptosis, Proto-oncogene that may play a role in differentiation and lymphopoiesis |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Proto-oncogene c-Rel, REL, C-Rel |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 2) Monoclonal, 3, C-rel (318CT41 |
| Short name | 2) Monoclonal Antibody, 3, C-rel (318CT41 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 2) monoclonal (Antibody to), 3, C-v-rel reticuloendotheliosis viral oncogene homolog (avian) (318CT41 |
| Alternative technique | antibodies |