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C-rel (318CT41.3.2) Monoclonal Antibody

C-rel (318CT41.3.2) Monoclonal Antibody size: 0.1ml 328

Price 328
Size 0.1ml
Long name2) Monoclonal Antibody, 3, C-rel (318CT41
Also known as2) Monoclonal Antibody, 3, C-rel (318CT41
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenC-rel
SpecificityThis is a highly specific antibody against C-rel
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number2, 3, 318CT41
SourceThis REL monoclonal antibody is generated from mouse immunized with REL recombinant protein
Gene ID number5966
Swiss ProtQ04864
Tested Applications IF, WB
Recommended dilutions IF(1:10~50), WB(1:500~16000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Different dimer combinations act as transcriptional activators or repressors, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, In a conventional activation pathway, NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family, NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52, RELB, The NF-kappa-B heterodimer RELA/p65-c-Rel is a transcriptional activator, The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity, cell growth, differentiation, immunity, respectively, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus, tumorigenesis and apoptosis, Proto-oncogene that may play a role in differentiation and lymphopoiesis
Purification method09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Proto-oncogene c-Rel, REL, C-Rel
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target2) Monoclonal, 3, C-rel (318CT41
Short name2) Monoclonal Antibody, 3, C-rel (318CT41
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name2) monoclonal (Antibody to), 3, C-v-rel reticuloendotheliosis viral oncogene homolog (avian) (318CT41
Alternative techniqueantibodies

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