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c-RET Antibody

c-RET Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenc-RET
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the RET antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis RET antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P07949
PurityPurified
Description Hirschsprung disease, Mutations i are associated with the disorders multiple endocrine neoplasia, This protein plays a crucial role in neural crest development, a member of the cadherin superfamily, and medullary thyroid carcinoma, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement, is one of the receptor tyrosine kinases, multiple endocrine neoplasia, type IIA, type IIB, which are cell-surface molecules that transduce signals for cell growth and differentiation, RET
ImmunogenA portion of amino acids 1012-1042 from the human protein was used as the immunogen for this RET antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RET antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetc-RET
Short namec-RET Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namec-ret proto-oncogene (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CDHF12 and CDHR16 and HSCR1 and MEN2A and MEN2B and MTC1 and PTC and RET-ELE1 and RET51, DNA-templated and biological process this GO :0048265 and response to pain and biological process this GO :0048484 and enteric nervous system development and biological process this GO :0050770 and regulation of axonogenesis and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060384 and innervation and biological process this GO :0061146 and Peyer's patch morphogenesis and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0072300 and positive regulation of metanephric glomerulus development and biological process this GO :0097021 and lymphocyte migration into lymphoid organs and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, Plasma membranes, RET and IDBG-628722 and ENSBTAG00000000570 and 515924, RET and IDBG-71064 and ENSG00000165731 and 5979, Ret and IDBG-181393 and ENSMUSG00000030110 and 19713, this GO :0000165 and MAPK cascade and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001838 and embryonic epithelial tube formation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007158 and neuron cell-cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007497 and posterior midgut development and biological process this GO :0010008 and endosome membrane and cellular component this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0014042 and positive regulation of neuron maturation and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0004872: receptor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0004872: receptor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030182 and neuron differentiation and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0033619 and membrane protein proteolysis and biological process this GO :0033630 and positive regulation of cell adhesion mediated by integrin and biological process this GO :0035799 and ureter maturation and biological process this GO :0042493 and response to drug and biological process this GO :0042551 and neuron maturation and biological process this GO :0043235 and receptor complex and cellular component this GO :0045121 and membrane raft and cellular component this GO :0045793 and positive regulation of cell size and biological process this GO :0045893 and positive regulation of transcription, ret proto-oncogene
Identity 9967
Gene RET
Long gene name ret proto-oncogene
Synonyms gene HSCR1 MEN2A MTC1 MEN2B
Synonyms gene name multiple endocrine neoplasia and medullary thyroid carcinoma 1 Hirschsprung disease 1
Synonyms PTC CDHF12 RET51 CDHR16
Synonyms name cadherin-related family member 16 RET receptor tyrosine kinase rearranged during transfection
Locus 10q11, 21
Discovery year 1990-07-15
GenBank acession BC004257
Entrez gene record 5979
Pubmed identfication 2687772 1611909
RefSeq identity NM_020975
Classification Cadherin related Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000018024
Locus Specific Databases LRG_518

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