| Long name | Cy5, 5 Conjugated, C-SKI/v-SKI Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | C-SKI/v-SKI |
| Specificity | This is a highly specific antibody against C-SKI/v-SKI |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human C-SKI |
| Gene ID number | 6497 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc, SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins, SKI represses Smad-mediated transcriptional activation, SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, The SKI oncoprotein dramatically affects cell growth, and tumor suppressors, and/or survival, differentiation, probably through its action as a transcriptional co-repressor, transforming growth factor beta, SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | C-SKI/v-SKI Conjugated |
| Short name | Conjugated, C-SKI/v-SKI Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, C-v-ski sarcoma viral oncogene homolog (avian)/v-v-ski sarcoma viral oncogene homolog (avian) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009948 and anterior/posterior axis specification and biological process this GO :0010467 and gene expression and biological process this GO :0010626 and negative regulation of Schwann cell proliferation and biological process this GO :0014902 and myotube differentiation and biological process this GO :0016604 and nuclear body and cellular component this GO :0016605 and PML body and cellular component this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0021772 and olfactory bulb development and biological process this GO :0022011 and myelination in peripheral nervous system and biological process this GO :0030177 and positive regulation of Wnt signaling pathway and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0031064 and negative regulation of histone deacetylation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032926 and negative regulation of activin receptor signaling pathway and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043234 and protein complex and cellular component this GO :0043388 and positive regulation of DNA binding and biological process this GO :0043585 and nose morphogenesis and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046811 and histone deacetylase inhibitor activity and molecular function this GO :0048147 and negative regulation of fibroblast proliferation and biological process this GO :0048593 and camera-type eye morphogenesis and biological process this GO :0048741 and skeletal muscle fiber development and biological process this GO :0048870 and cell motility and biological process this GO :0060021 and palate development and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060325 and face morphogenesis and biological process this GO :0060349 and bone morphogenesis and biological process this GO :0060395 and SMAD protein signal transduction and biological process this GO :0070207 and protein homotrimerization and biological process this GO :0070491 and repressing transcription factor binding and molecular function, SGS and SKV, SKI and IDBG-634866 and ENSBTAG00000038716 and 506127, SKI and IDBG-86169 and ENSG00000157933 and 6497, Ski and IDBG-207475 and ENSMUSG00000029050 and 20481, nuclei, repressing transcription factor binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001843 and neural tube closure and biological process this GO :0002089 and lens morphogenesis in camera-type eye and biological process this GO :0003682 and chromatin binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0006351 and transcription, this GO :0003682: chromatin binding, this GO :0003682: chromatin binding and also this GO :0003714: transcription corepressor activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0019901: protein kinase binding and also this GO :0019904: protein domain specific binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0046332: SMAD binding and also this GO :0046811: histone deacetylase inhibitor activity and also this GO :0070491: repressing transcription factor binding, this GO :0003714: transcription corepressor activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0019901: protein kinase binding, this GO :0019904: protein domain specific binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0046332: SMAD binding, this GO :0046811: histone deacetylase inhibitor activity, this GO :0070491: repressing transcription factor binding, v-ski sarcoma viral oncogene homolog (avian) |
| Identity | 10896 |
| Gene | SKI |
| Long gene name | SKI proto-oncogene |
| Synonyms gene name | v-ski avian sarcoma viral oncogene homolog |
| Locus | 1p36, 32 , 33-p36 |
| Discovery year | 2001-06-22 |
| GenBank acession | X15218 |
| Entrez gene record | 6497 |
| Pubmed identfication | 2762147 |
| RefSeq identity | NM_003036 |
| Classification | SKI transcriptional corepressors |
| Havana BLAST/BLAT | OTTHUMG00000001407 |
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