Name : C18orf1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN1571430206
| Long name | C18orf1 Primary Polyclonal Antibody |
| Also known as | C18orf1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | C18orf1 |
| Specificity | This is a highly specific antibody against C18orf1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1-50/306 |
| Subcellular location | Lumenal |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C18orf1 |
| Gene ID number | 753 |
| Swiss Prot | O15165 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In the canonical TGF-beta pathway, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal, Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription, Through interaction with SMAD2 and SMAD3, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor, apoptosis, differentiation, extracellular matrix production and immunosuppression, motility, Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | LDLRAD4, Low-density lipoprotein receptor class A domain-containing protein 4, C18orf1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | C18orf1 |
| Short name | C18orf1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | C18orf1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1224 |
| Gene | LDLRAD4 |
| Long gene name | low density lipoprotein receptor class A domain containing 4 |
| Synonyms gene | C18orf1 |
| Synonyms gene name | chromosome 18 open reading frame 1 |
| Synonyms name | clone 22 |
| Locus | 18p11, 21 |
| Discovery year | 1998-08-06 |
| GenBank acession | AF009424 AF009428 |
| Entrez gene record | 753 |
| Pubmed identfication | 9479497 9129712 24627487 |
| RefSeq identity | NM_181481 |
| Havana BLAST/BLAT | OTTHUMG00000181925 |