Name : C18orf1 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8388542756
| Long name | ALEXA FLUOR 647 Conjugated, C18orf1 Polyclonal Antibody |
| Also known as | Anti-C18orf1 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | C18orf1 |
| Specificity | This is a highly specific antibody against C18orf1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1-50/306 |
| Subcellular location | Lumenal |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C18orf1 |
| Gene ID Number | 753 |
| Swiss Prot | O15165 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | In the canonical TGF-beta pathway, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal, Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription, Through interaction with SMAD2 and SMAD3, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor, apoptosis, differentiation, extracellular matrix production and immunosuppression, motility, Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the C18orf1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | C18orf1 |
| Short name | C18orf1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, C18orf1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1224 |
| Gene | LDLRAD4 |
| Long gene name | low density lipoprotein receptor class A domain containing 4 |
| Synonyms gene | C18orf1 |
| Synonyms gene name | chromosome 18 open reading frame 1 |
| Synonyms name | clone 22 |
| Locus | 18p11, 21 |
| Discovery year | 1998-08-06 |
| GenBank acession | AF009424 AF009428 |
| Entrez gene record | 753 |
| Pubmed identfication | 9479497 9129712 24627487 |
| RefSeq identity | NM_181481 |
| Havana BLAST/BLAT | OTTHUMG00000181925 |