Name : C2CD3 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4472783921
| Long name | ALEXA FLUOR 350 Conjugated, C2CD3 Polyclonal Antibody |
| Also known as | Anti-C2CD3 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | C2CD3 |
| Specificity | This is a highly specific antibody against C2CD3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C2CD3 |
| Gene ID Number | 26005 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Atm mutation leads to the disorder known as ataxia-telangiectasia, C2 domains are regions of about 130 amino acid residues that are found in proteins that bind phospholipids, C2CD3 is expressed as five isoforms produced by alternative splicing events, It is thought that calcium binding to the C2 domain induces an electrostatic potential change that enhances phospholipid binding, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The blood disorders Sickle cell anemia and Î, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, The gene that encodes C2CD3 maps to human chromosome 11, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, Wilms' tumors, also known as FLJ34770, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, is a 2, thalassemia are caused by HBB gene mutations, which makes up around 4% of human genomic DNA, which suggests a role for the domain as an electrostatic switch, ², 353 amino acid protein that contains two C2 domains, C2CD3 (C2 domain-containing protein 3) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | DKFZP586P0123 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | C2CD3 |
| Short name | C2CD3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, C2CD3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24564 |
| Gene | C2CD3 |
| Long gene name | C2 calcium dependent domain containing 3 |
| Locus | 11q13, 4 |
| Discovery year | 2007-10-17 |
| GenBank acession | BC035599 |
| Entrez gene record | 26005 |
| RefSeq identity | NM_015531 |
| Classification | C2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000168110 |