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C2CD3 Antibody, ALEXA FLUOR 488

C2CD3 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, C2CD3 Polyclonal Antibody
Also known asAnti-C2CD3 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenC2CD3
SpecificityThis is a highly specific antibody against C2CD3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C2CD3
Gene ID Number26005
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Atm mutation leads to the disorder known as ataxia-telangiectasia, C2 domains are regions of about 130 amino acid residues that are found in proteins that bind phospholipids, C2CD3 is expressed as five isoforms produced by alternative splicing events, It is thought that calcium binding to the C2 domain induces an electrostatic potential change that enhances phospholipid binding, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The blood disorders Sickle cell anemia and Î, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, The gene that encodes C2CD3 maps to human chromosome 11, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, Wilms' tumors, also known as FLJ34770, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, is a 2, thalassemia are caused by HBB gene mutations, which makes up around 4% of human genomic DNA, which suggests a role for the domain as an electrostatic switch, ², 353 amino acid protein that contains two C2 domains, C2CD3 (C2 domain-containing protein 3)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms DKFZP586P0123
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the C2CD3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetC2CD3
Short nameC2CD3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, C2CD3 (Antibody to)
Alternative techniqueantibodies
Identity 24564
Gene C2CD3
Long gene name C2 calcium dependent domain containing 3
Locus 11q13, 4
Discovery year 2007-10-17
GenBank acession BC035599
Entrez gene record 26005
RefSeq identity NM_015531
Classification C2 domain containing
Havana BLAST/BLAT OTTHUMG00000168110

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