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C2CD3 Antibody, FITC Conjugated

C2CD3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, C2CD3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenC2CD3
SpecificityThis is a highly specific antibody against C2CD3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human C2CD3
Gene ID number26005
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Atm mutation leads to the disorder known as ataxia-telangiectasia, C2 domains are regions of about 130 amino acid residues that are found in proteins that bind phospholipids, C2CD3 is expressed as five isoforms produced by alternative splicing events, It is thought that calcium binding to the C2 domain induces an electrostatic potential change that enhances phospholipid binding, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The blood disorders Sickle cell anemia and Î, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, The gene that encodes C2CD3 maps to human chromosome 11, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, Wilms' tumors, also known as FLJ34770, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, is a 2, thalassemia are caused by HBB gene mutations, which makes up around 4% of human genomic DNA, which suggests a role for the domain as an electrostatic switch, ², 353 amino acid protein that contains two C2 domains, C2CD3 (C2 domain-containing protein 3)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms DKFZP586P0123
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetC2CD3 Conjugated
Short name FITC Conjugated, C2CD3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, C2CD3 (Antibody to)
Alternative techniqueantibodies
Identity 24564
Gene C2CD3
Long gene name C2 calcium dependent domain containing 3
Locus 11q13, 4
Discovery year 2007-10-17
GenBank acession BC035599
Entrez gene record 26005
RefSeq identity NM_015531
Classification C2 domain containing
Havana BLAST/BLAT OTTHUMG00000168110

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