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C5a Antibody Complement 5a

C5a Antibody Complement 5a size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenC5a Complement 5a
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the C5a antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis C5a antibodyis to be used only for research purposes and not for diagnostics
Gene ID #362119
PurityAntigen affinity
Description An activation peptide, C5a, Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis, Mutations in this gene cause complement component 5 deficiency, The C5b macromolecular cleavage product can form a complex with the C6 complement component, The protein encoded by this gene is the fifth component of complement, This gene is mapped to 9q33, This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge, a disease where patients show a propensity for severe recurrent infections, and this complex is the basis for formation of the membrane attack complex, is derived from the alpha polypeptide via cleavage with a convertase, which includes additional complement components, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, which plays an important role in inflammatory and cell killing processes, 2, C5a is a protein fragment released from complement component C5
ImmunogenAn amino acid sequence from the N-terminus of rat Complement 5a (DLQLLHQKVEEQAAKYKH) was used as the immunogen for this C5a antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the C5a antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetC5a Complement 5a
Short nameC5a Antibody Complement 5a
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameC5a (Antibody to) Complement 5a
Alternative techniqueantibodies
Identity 1338
Gene C5AR1
Long gene name complement C5a receptor 1
Synonyms gene C5R1
Synonyms gene name complement component 5 receptor 1 (C5a ligand) complement component 5a receptor 1
Synonyms C5A C5AR CD88
Locus 19q13, 32
Discovery year 1991-12-04
Entrez gene record 728
Pubmed identfication 1612600
RefSeq identity NM_001736
Classification Complement component GPCRs Complement system CD molecules
Havana BLAST/BLAT OTTHUMG00000183504

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