Name : CABC1 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9461568622
| Long name | ALEXA FLUOR 350 Conjugated, CABC1 Polyclonal Antibody |
| Also known as | Anti-CABC1 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CABC1 |
| Specificity | This is a highly specific antibody against CABC1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADCK3/CABC1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | CoQ10 deficiency is an autosomal recessive disorder with variable manifestations, It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, Patients can manifest brisk tendon reflexes and Hoffmann sign, Patients show progressive incoordination of gait and often poor coordination of hands, SCAR9 is an autosomal recessive form characterized by gait ataxia and cerebellar atrophy with slow progression and few associated features, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, also known as autosomal recessive cerebellar ataxia type 2 (ARCA2), an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, exercise intolerance and elevated serum lactate, mild axonal degeneration of the sural nerve, mild psychomotor retardation, speech and eye movements, Defects in ADCK3 are the cause of spinocerebellar ataxia autosomal recessive type 9 (SCAR9) [MIM:612016], Involvement in disease:Defects in ADCK3 are a cause of coenzyme Q10 deficiency (CoQ10 deficiency), May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain, Tissue specificity:Ubiquitously expressed with a relatively greater abundance in heart and skeletal muscle |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | COQ8 SCAR9 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | CABC1 |
| Short name | CABC1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, CABC1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16812 |
| Gene | COQ8A |
| Long gene name | coenzyme Q8A |
| Synonyms gene | CABC1 ADCK3 |
| Synonyms gene name | ABC1 activity of bc1 complex homolog (S, ABC1 activity of bc1 complex like (S, S, chaperone-ABC1 (activity of bc1 complex, pombe) aarF domain containing kinase 3 , pombe) chaperone, pombe)-like chaperone |
| Synonyms name | coenzyme Q8 homolog (yeast) |
| Locus | 1q42, 13 |
| Discovery year | 2001-10-31 |
| GenBank acession | AJ278126 |
| Entrez gene record | 56997 |
| Pubmed identfication | 18319072 18319074 25498144 |
| RefSeq identity | NM_020247 |
| Havana BLAST/BLAT | OTTHUMG00000037621 |
| Locus Specific Databases | LRG_1092 |