Name : CABC1 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8109339152
| Long name | Cy3 Conjugated, CABC1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CABC1 |
| Specificity | This is a highly specific antibody against CABC1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human ADCK3/CABC1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CoQ10 deficiency is an autosomal recessive disorder with variable manifestations, It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, Patients can manifest brisk tendon reflexes and Hoffmann sign, Patients show progressive incoordination of gait and often poor coordination of hands, SCAR9 is an autosomal recessive form characterized by gait ataxia and cerebellar atrophy with slow progression and few associated features, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, also known as autosomal recessive cerebellar ataxia type 2 (ARCA2), an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, exercise intolerance and elevated serum lactate, mild axonal degeneration of the sural nerve, mild psychomotor retardation, speech and eye movements, Defects in ADCK3 are the cause of spinocerebellar ataxia autosomal recessive type 9 (SCAR9) [MIM:612016], Involvement in disease:Defects in ADCK3 are a cause of coenzyme Q10 deficiency (CoQ10 deficiency), May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain, Tissue specificity:Ubiquitously expressed with a relatively greater abundance in heart and skeletal muscle |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | COQ8 SCAR9 |
| Properties | 1 of the CABC1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CABC1 Conjugated |
| Short name | Conjugated, CABC1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, CABC1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16812 |
| Gene | COQ8A |
| Long gene name | coenzyme Q8A |
| Synonyms gene | CABC1 ADCK3 |
| Synonyms gene name | ABC1 activity of bc1 complex homolog (S, ABC1 activity of bc1 complex like (S, S, chaperone-ABC1 (activity of bc1 complex, pombe) aarF domain containing kinase 3 , pombe) chaperone, pombe)-like chaperone |
| Synonyms name | coenzyme Q8 homolog (yeast) |
| Locus | 1q42, 13 |
| Discovery year | 2001-10-31 |
| GenBank acession | AJ278126 |
| Entrez gene record | 56997 |
| Pubmed identfication | 18319072 18319074 25498144 |
| RefSeq identity | NM_020247 |
| Havana BLAST/BLAT | OTTHUMG00000037621 |
| Locus Specific Databases | LRG_1092 |