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CACNA1B (N type) Antibody, Biotin Conjugated

CACNA1B (N type) Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CACNA1B (N type) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCACNA1B N type
SpecificityThis is a highly specific antibody against CACNA1B N type
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range115-132/2339
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human CACNA1B (N type)
Gene ID number774
Swiss ProtQ00975
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons, N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin-IIIA (omega-Aga-IIIA), The isoform alpha-1B gives rise to N-type calcium currents, They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA), cell division and cell death, cell motility, gene expression, hormone or neurotransmitter release, including muscle contraction, Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Cav2, 2 CACNN
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCACNA1B (N Conjugated
Short name Conjugated, CACNA1B (N type) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CACNA1B (N classification) (Antibody to)
Alternative techniqueantibodies
Identity 1389
Gene CACNA1B
Long gene name calcium voltage-gated channel subunit alpha1 B
Synonyms gene CACNL1A5
Synonyms gene name N type, alpha 1B subunit , calcium channel, voltage-dependent
Locus 9q34, 3
Discovery year 1995-06-01
GenBank acession AB209467
Entrez gene record 774
Pubmed identfication 8825650 16382099
RefSeq identity NM_000718
Classification Calcium voltage-gated channel subunits EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000021002

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