Name : CACNA1S Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN7603159787
| Long name | CACNA1S Primary Polyclonal Antibody |
| Also known as | CACNA1S PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CACNA1S |
| Specificity | This is a highly specific antibody against CACNA1S |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 951-1001/1873 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CACNA1S |
| Gene ID number | 779 |
| Swiss Prot | Q13698 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle, Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group, The isoform alpha-1S gives rise to L-type calcium currents, They are blocked by dihydropyridines (DHP), They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA), and by omega-agatoxin-IIIA (omega-Aga-IIIA), benzothiazepines, cell division and cell death, cell motility, gene expression, hormone or neurotransmitter release, including muscle contraction, phenylalkylamines, Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CACH1, CACN1, CACNA1S, CACNL1A3, Calcium channel, L type, Voltage-gated calcium channel subunit alpha Cav1, alpha-1 polypeptide, isoform 3, skeletal muscle, 1, Voltage-dependent L-type calcium channel subunit alpha-1S |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CACNA1S |
| Short name | CACNA1S Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CACNA1S (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1397 |
| Gene | CACNA1S |
| Long gene name | calcium voltage-gated channel subunit alpha1 S |
| Synonyms gene | HOKPP MHS5 CACNL1A3 |
| Synonyms gene name | L type, alpha 1S subunit , calcium channel, voltage-dependent |
| Synonyms | Cav1, 1 hypoPP |
| Locus | 1q32, 1 |
| Discovery year | 1992-03-27 |
| GenBank acession | L33798 |
| Entrez gene record | 779 |
| Pubmed identfication | 7916735 16382099 |
| RefSeq identity | NM_000069 |
| Classification | Calcium voltage-gated channel subunits |
| Havana BLAST/BLAT | OTTHUMG00000035784 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database |