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CACNA1S Antibody, Biotin Conjugated

CACNA1S Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, CACNA1S Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCACNA1S
SpecificityThis is a highly specific antibody against CACNA1S
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range951-1001/1873
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human CACNA1S
Gene ID number779
Swiss ProtQ13698
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle, Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group, The isoform alpha-1S gives rise to L-type calcium currents, They are blocked by dihydropyridines (DHP), They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA), and by omega-agatoxin-IIIA (omega-Aga-IIIA), benzothiazepines, cell division and cell death, cell motility, gene expression, hormone or neurotransmitter release, including muscle contraction, phenylalkylamines, Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Cav1, 1 hypoPP
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCACNA1S Conjugated
Short name Conjugated, CACNA1S Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CACNA1S (Antibody to)
Alternative techniqueantibodies
Identity 1397
Gene CACNA1S
Long gene name calcium voltage-gated channel subunit alpha1 S
Synonyms gene HOKPP MHS5 CACNL1A3
Synonyms gene name L type, alpha 1S subunit , calcium channel, voltage-dependent
Locus 1q32, 1
Discovery year 1992-03-27
GenBank acession L33798
Entrez gene record 779
Pubmed identfication 7916735 16382099
RefSeq identity NM_000069
Classification Calcium voltage-gated channel subunits
Havana BLAST/BLAT OTTHUMG00000035784
Locus Specific Databases LOVD - Leiden Open Variation Database

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