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CACNA1S Antibody, FITC Conjugated

CACNA1S Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, CACNA1S Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCACNA1S
SpecificityThis is a highly specific antibody against CACNA1S
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range951-1001/1873
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human CACNA1S
Gene ID number779
Swiss ProtQ13698
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle, Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group, The isoform alpha-1S gives rise to L-type calcium currents, They are blocked by dihydropyridines (DHP), They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA), and by omega-agatoxin-IIIA (omega-Aga-IIIA), benzothiazepines, cell division and cell death, cell motility, gene expression, hormone or neurotransmitter release, including muscle contraction, phenylalkylamines, Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms Cav1, 1 hypoPP
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCACNA1S Conjugated
Short name FITC Conjugated, CACNA1S Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, CACNA1S (Antibody to)
Alternative techniqueantibodies
Identity 1397
Gene CACNA1S
Long gene name calcium voltage-gated channel subunit alpha1 S
Synonyms gene HOKPP MHS5 CACNL1A3
Synonyms gene name L type, alpha 1S subunit , calcium channel, voltage-dependent
Locus 1q32, 1
Discovery year 1992-03-27
GenBank acession L33798
Entrez gene record 779
Pubmed identfication 7916735 16382099
RefSeq identity NM_000069
Classification Calcium voltage-gated channel subunits
Havana BLAST/BLAT OTTHUMG00000035784
Locus Specific Databases LOVD - Leiden Open Variation Database

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