Name : CAD Antibody
Supplier : NJS POLY
Price :199
SKU : GEN3131575930
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CAD |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the CAD antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This CAD antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P27708 |
| Purity | Antigen affinity |
| Description | This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, and dihydroorotase, aspartate transcarbamoylase, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides, The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate |
| Immunogen | A portion of amino acids 780-809 from the human protein was used as the immunogen for this CAD antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CAD antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CAD |
| Short name | CAD Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CAD (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1424 |
| Gene | CAD |
| Long gene name | and dihydroorotase , aspartate transcarbamylase, carbamoyl-phosphate synthetase 2 |
| Locus | 2p23, 3 |
| Discovery year | 2001-06-22 |
| GenBank acession | D78586 |
| Entrez gene record | 790 |
| Pubmed identfication | 8619816 2565865 |
| Havana BLAST/BLAT | OTTHUMG00000097070 |