Filters

CADPS2 Antibody, FITC Conjugated

CADPS2 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, CADPS2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCADPS2
SpecificityThis is a highly specific antibody against CADPS2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CADPS2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances, CAPS proteins help to regulate cell fate during neuronal development, CAPS-1 is thought to regulate catecholamine release from neuronal cells, Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism, The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, Through their regulation of neurotrophin release from granule cells, as well as regulation of phospholipid binding, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells, Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CAPS2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCADPS2 Conjugated
Short name FITC Conjugated, CADPS2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Ca+and-dependent secretion activator 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CADPS2 and IDBG-38565 and ENSG00000081803 and 93664, CADPS2 and IDBG-634757 and ENSBTAG00000005110 and 519444, Cadps2 and IDBG-129779 and ENSMUSG00000017978 and 320405, Cell surfaces, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0008289 and lipid binding and molecular function this GO :0009267 and cellular response to starvation and biological process this GO :0015031 and protein transport and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016082 and synaptic vesicle priming and biological process this GO :0030054 and cell junction and cellular component this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0042734 and presynaptic membrane and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0045921 and positive regulation of exocytosis and biological process this GO :0046872 and metal ion binding and molecular function, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008289: lipid binding and also this GO :0046872: metal ion binding, this GO :0008289: lipid binding, this GO :0046872: metal ion binding, Ca++-dependent secretion activator 2
Identity 16018
Gene CADPS2
Long gene name calcium dependent secretion activator 2
Synonyms gene name Ca++-dependent activator protein for secretion 2 Ca2+ dependent secretion activator 2
Locus 7q31, 32
Discovery year 2001-07-12
Entrez gene record 93664
RefSeq identity NM_017954
Classification Pleckstrin homology domain containing C2 domain containing
Havana BLAST/BLAT OTTHUMG00000157093

Subscribe to our Newsletter