Name : Caldesmon / CAD Antibody
Supplier : NJS POLY
Price :406
SKU : GEN8505077552
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Caldesmon / CAD |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (FFPE): 0, Western blot: 0 |
| Notes | Optimal dilution of the Caldesmon antibody should be determined by the researcher |
| Intented use | This Caldesmon antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q05682 |
| Purity | Antigen affinity |
| Description | Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms, It is mapped to 7q33, The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction, This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, actin, and phospholipids, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction, myosin, tropomyosin, Caldesmon is a protein that in humans is encoded by the CALD1 gene |
| Immunogen | Amino acids M1-E120 of the human protein were used as the immunogen for the Caldesmon antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Caldesmon antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Caldesmon / CAD |
| Short name | Caldesmon / CAD Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Caldesmon / CAD (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1424 |
| Gene | CAD |
| Long gene name | and dihydroorotase , aspartate transcarbamylase, carbamoyl-phosphate synthetase 2 |
| Locus | 2p23, 3 |
| Discovery year | 2001-06-22 |
| GenBank acession | D78586 |
| Entrez gene record | 790 |
| Pubmed identfication | 8619816 2565865 |
| Havana BLAST/BLAT | OTTHUMG00000097070 |