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CALHM1/FAM26C Antibody

CALHM1/FAM26C Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCALHM1/FAM26C Primary Polyclonal Antibody
Also known asCALHM1/FAM26C PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCALHM1/FAM26C
SpecificityThis is a highly specific antibody against CALHM1/FAM26C
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CALHM1/FAM26C
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CALHM1 co-localizes with GRP 78 to the endoplasmic reticulum, CALHM1 homomultimerizes and shares strong sequence similarities with the selectivity filter of the NMDA receptor, CALHM1 may be a pore-forming ion channel that controls cytosolic Ca2+ permeability and cytosolic Ca2+ concentration in the cell, CALHM1 may be a potential factor involved in the pathogenesis of Alzheimer's disease, It is suggested that CALHM1 regulates amyloid precursor protein proteolysis and aggregated amyloid-beta peptides levels in a Ca2+ dependent manner, Predominantly expressed in adult brain, which generates a large Ca2+ conductance across the plasma membrane, CALHM1 is a 346 amino acid multi-pass endoplasmic reticulum membrane protein that belongs to the FAM26 family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CALHM1, Calcium homeostasis modulator 1, Calcium homeostasis modulator protein 1, FAM26C, Family with sequence similarity 26, MGC39514, MGC39617, Protein FAM26C, member C, CAHM1_HUMAN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCALHM1/FAM26C
Short nameCALHM1/FAM26C Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCALHM1/FAM26C (Antibody to)
Alternative techniqueantibodies
Identity 23494
Gene CALHM1
Long gene name calcium homeostasis modulator 1
Synonyms gene FAM26C
Synonyms gene name family with sequence similarity 26, member C
Locus 10q24, 33
Discovery year 2004-05-27
GenBank acession BC036208
Entrez gene record 255022
Pubmed identfication 18585350
RefSeq identity NM_001001412
Havana BLAST/BLAT OTTHUMG00000018991

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