Name : CALHM1/FAM26C Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6587251155
| Long name | ALEXA FLUOR 594 Conjugated, CALHM1/FAM26C Polyclonal Antibody |
| Also known as | Anti-CALHM1/FAM26C PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CALHM1/FAM26C |
| Specificity | This is a highly specific antibody against CALHM1/FAM26C |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CALHM1/FAM26C |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | CALHM1 co-localizes with GRP 78 to the endoplasmic reticulum, CALHM1 homomultimerizes and shares strong sequence similarities with the selectivity filter of the NMDA receptor, CALHM1 may be a pore-forming ion channel that controls cytosolic Ca2+ permeability and cytosolic Ca2+ concentration in the cell, CALHM1 may be a potential factor involved in the pathogenesis of Alzheimer's disease, It is suggested that CALHM1 regulates amyloid precursor protein proteolysis and aggregated amyloid-beta peptides levels in a Ca2+ dependent manner, Predominantly expressed in adult brain, which generates a large Ca2+ conductance across the plasma membrane, CALHM1 is a 346 amino acid multi-pass endoplasmic reticulum membrane protein that belongs to the FAM26 family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | CALHM1/FAM26C |
| Short name | CALHM1/FAM26C Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, CALHM1/FAM26C (Antibody to) |
| Alternative technique | antibodies |
| Identity | 23494 |
| Gene | CALHM1 |
| Long gene name | calcium homeostasis modulator 1 |
| Synonyms gene | FAM26C |
| Synonyms gene name | family with sequence similarity 26, member C |
| Locus | 10q24, 33 |
| Discovery year | 2004-05-27 |
| GenBank acession | BC036208 |
| Entrez gene record | 255022 |
| Pubmed identfication | 18585350 |
| RefSeq identity | NM_001001412 |
| Havana BLAST/BLAT | OTTHUMG00000018991 |