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CALHM1/FAM26C Antibody, Biotin Conjugated

CALHM1/FAM26C Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CALHM1/FAM26C Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCALHM1/FAM26C
SpecificityThis is a highly specific antibody against CALHM1/FAM26C
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CALHM1/FAM26C
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CALHM1 co-localizes with GRP 78 to the endoplasmic reticulum, CALHM1 homomultimerizes and shares strong sequence similarities with the selectivity filter of the NMDA receptor, CALHM1 may be a pore-forming ion channel that controls cytosolic Ca2+ permeability and cytosolic Ca2+ concentration in the cell, CALHM1 may be a potential factor involved in the pathogenesis of Alzheimer's disease, It is suggested that CALHM1 regulates amyloid precursor protein proteolysis and aggregated amyloid-beta peptides levels in a Ca2+ dependent manner, Predominantly expressed in adult brain, which generates a large Ca2+ conductance across the plasma membrane, CALHM1 is a 346 amino acid multi-pass endoplasmic reticulum membrane protein that belongs to the FAM26 family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCALHM1/FAM26C Conjugated
Short name Conjugated, CALHM1/FAM26C Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CALHM1/FAM26C (Antibody to)
Alternative techniqueantibodies
Identity 23494
Gene CALHM1
Long gene name calcium homeostasis modulator 1
Synonyms gene FAM26C
Synonyms gene name family with sequence similarity 26, member C
Locus 10q24, 33
Discovery year 2004-05-27
GenBank acession BC036208
Entrez gene record 255022
Pubmed identfication 18585350
RefSeq identity NM_001001412
Havana BLAST/BLAT OTTHUMG00000018991

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