Filters

CAPON Antibody, ALEXA FLUOR 488

CAPON Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, CAPON Polyclonal Antibody
Also known asAnti-CAPON PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCAPON
SpecificityThis is a highly specific antibody against CAPON
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CAPON
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, The association of nNOS with PSD95 or PSD93 is regulated by CAPON, The carboxy terminus of CAPON binds to the PDZ domain, These proteins facilitate the transport of nNOS to the plasma membrane, and sequesters nNOS in the cytosol, but not to endothelial NOS or inducible NOS, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain, where it is catalytically activated by NMDA-receptor mediated calcium channels, CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms KIAA0464 CAPON
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CAPON Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetCAPON
Short nameCAPON Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, CAPON (Antibody to)
Alternative techniqueantibodies
Identity 16859
Gene NOS1AP
Long gene name nitric oxide synthase 1 adaptor protein
Synonyms gene name nitric oxide synthase 1 (neuronal) adaptor protein
Synonyms name C-terminal PDZ domain ligand of neuronal nitric oxide synthase
Locus 1q23, 3
Discovery year 2005-06-15
GenBank acession AB007933
Entrez gene record 9722
Pubmed identfication 9455484 9459447
RefSeq identity NM_014697
Havana BLAST/BLAT OTTHUMG00000024049

Similar products

Subscribe to our Newsletter